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Augmentin is one of the most popular antibacterial antibiotics, which includes two components that interact very effectively with each other, making Augmentin a very effective drug in the treatment of diseases. The first and main component is Amoxicillin, which is a penicillin antibiotic that has a wide range of activity against many microorganisms. The second is Clavulanate Acid. The presence of this acid in the preparation protects Amoxicillin from decay, expanding the spectrum of antibacterial action.

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What is Augmentin

The antibiotic Augmentin is used to fight various bacterial infections, this drug is one of the most common means of this kind in the world. It is prescribed by doctors for the treatment of acute respiratory diseases. The great advantage of this drug is that it can be used in the treatment of adults, as well as in the treatment of children, that is, this drug is suitable for everyone without exception.

Augmentin is an original development and is a combination of Amoxicillin — one of the best antibiotics of the penicillin series — and the most powerful of the known inhibitors of beta-lactamase - Clavulanate Acid. The combination of these two components in Augmentin leads to the appearance of special properties.

The drug implements the concept of "Attacking, Defending": Clavulanic acid irreversibly blocks the β-lactamases of both pathogenic and non-pathogenic microorganisms, opening a free path for Amoxicillin to attack infectious agents. Such properties have allowed the drug to show high clinical efficacy in many infections of various organs and systems, which does not change with time, as evidenced by more than 25 years of experience of successful use worldwide. With the advent of Augmentin came the Renaissance of penicillin antibiotics. They are restored to their rights, and deservedly so.

Recommendations for taking tablets

Augmentin tablets are advised to drink before meals, not mixing with food, as there is a deactivation of up to 15% of the active substance, which reduces the dose of the drug in the blood. As a result, the necessary dose of the desired effect of taking an antibiotic falls. This can be especially fraught in the treatment of severe infections.

The use of Augmentin

The use of Augmentin in practice among people of different ages and animals has a solid evidence base. For this original antibiotic that has gone through numerous clinical studies confirming its effectiveness in the treatment of respiratory infections. The high effectiveness of the drug Augmentin in various infections has been proven in controlled studies involving tens of thousands of patients for about 30 years. In total, there are about seventy thousand publications in the world today that describe the successful use of Augmentin in the treatment of diseases, which makes It perhaps the most studied antibiotic in the world after penicillin. Another surprising feature of the drug that distinguishes it from other modern antimicrobial agents and antibiotics was also revealed - despite the fact that the drug has been used since 1980, the sensitivity of microorganisms to Augmentin has not changed.

The field of application of Augmentin is wide due to its high ability to bactericidal effect on aerobic and anaerobic flora (both gram-positive and gram-negative). A wide range of Augmentin activity allows for monotherapy with this drug even in cases where, in its absence, it was necessary to use a combination of two or more antibiotics. This reduces the incidence of adverse reactions and deprives microorganisms of the ability to produce resistant strains.

Doctors prescribe Augmentin in the event that bacterial infection has undergone various parts of the body, such as:

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  • Lower respiratory tract - tonsillitis, sinusitis, otitis media, exacerbation of chronic bronchitis, pneumonia;
  • Upper air passages;
  • ENT organs;
  • Skin and soft tissues of the body;
  • Infections of the genitourinary system - cystitis, urethritis, pyelonephritis, sexually transmitted infections, gynecological and obstetric infections;
  • Male and female genitals;
  • Bones and joints;
  • Teeth and oral cavity;
  • And also for perioperative prophylaxis of surgical infection.

In addition to the high clinical and bacteriological efficacy, which persists over time, Augmentin has a favorable safety and tolerability profile. Therefore, it is not surprising that Augmentin received the deserved recognition of doctors. It is registered and applied almost all over the world. At the same time, in the guidelines for antibiotic therapy in many developed countries, Augmentin is recommended as a first-choice antibiotic for the empirical therapy of various infections.

The recognition of the high effectiveness of Augmentin is evidenced by the fact that in 1995 the national Committee for clinical laboratory Standards of the USA (National Committee for Clinical Laboratory Standards) declared Augmentin the gold standard among penicillin antibiotics, that is, the one with which all newly created antibiotics are compared (Legnani D. 1997). Despite the duration of the use of Augmentin in clinical practice, it is not inferior in effectiveness to many newly created anti-microbial agents.

Strength in constant development

The company's specialists did not stop there: new treatment regimens, new dosages, new dosage forms were developed. Such innovations did not go unnoticed, and in 1986 the scientists-developers of AUGMENTIN were awarded the Queen's award of great Britain, the Galen prize in France and the award of the government of Spain.

Contraindications to taking

Let's move on to the reverse side of this antibiotic, despite all its advantages, the drug is a pharmacological agent and all pharmacological agents have contraindications and Augmentin is no exception.

Augmentin can not be used with allergies to any antibiotic-penicillin, the presence in the past of severe allergic reactions associated with the use of antibiotics, the presence in the past of liver disorders or jaundice associated with the reception of Amoxicillin, Clavulanic acid.

Animal studies of different dosage forms of Augmentin have not revealed teratogenic effects (disorders of embryo development). The use of Augmentin in pregnant women may increase the risk of necrotizing enterocolitis (inflammation and death of the mucous membrane of the small and large intestine) in newborns. Therefore, it should be avoided during pregnancy, especially in the first trimester.

Additional Information

Augmentin is considered an excellent treatment for bacterial infection of the tonsils, i.e. angina. In the treatment of angina, the drug is taken in a dosage of 875 mg once a day or 500 mg 3 times a day. The duration of treatment for angina is 7-8 days.

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  • Never take Augmentin without a doctor's prescription! Only a specialist can distinguish a viral infection from a bacterial infection and prescribe a course of proper antibiotics;
  • Do not take Augmentin for prophylactic purposes. For example, some people start taking antibiotics immediately for SARS-so as not to wait for bacterial complications of a viral infection. Such prevention can lead to the opposite effect: bacteria that are resistant to the antibiotic will grow;
  • Augmentin have a number of side effects. Among them – dehydration, intestinal disorders, allergic reactions. Side effects may increase if you continue to run on a course of antibiotics;
  • Do not use Augmentin with expired shelf life remaining from the previous treatment. Such drugs are dangerous to health.

Small doses of the drug are used for the treatment of skin infections, and large portions are prescribed for the treatment of upper and lower respiratory tract infections. The drug is incompatible with blood products containing protein, it is forbidden to mix the drug with a dropper with aminoglycoside antibiotics, because inactivation occurs.

Method of application

Augmentin should be used after the study of antibiotic sensitivity. Treatment should not be continued for more than 14 days without a comprehensive assessment of the patient's condition. This drug is available without a prescription.

The outcome of the disease depends not only on the correct choice of the drug, but also on the strict observance of the multiplicity of its application. This is one of the reasons for the error of treatment, because often patients miss the time of taking the next dose of the drug. The use of a new dosage form Augmentin 1000 mg will reduce the frequency of taking the drug up to 2 times a day, which is undoubtedly more convenient for the patient. Augmentin 1000 mg when taken 2 times a day is an effective and convenient treatment option for patients with severe respiratory tract infections.

Tablets Augmentin adult patients and children weight-appoint a dose of 500 mg / 125 mg x 3 times a day. Children weighing 25-40 kg - from 20 mg/5 mg/kg to 60 mg/15 mg/kg per day in 3 doses.

Conditions and terms of storage at temperatures up to 25°C. the Finished suspension should be stored at 2-8 °C and used up to 7 days. Shelf life of Augmentin - 2 year.


Augmentin rightfully occupies one of the leading places among the means for empirical antibiotic therapy of patients due to its high efficiency, reliability, safety and importantly, affordability for the people of our planet.

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